Mikhail Blagosklonny Develops TOR Hypothesis for Cancer Treatment


Medical Science is known to have prolonged the standard human lifespan. Since the public health programmes for the treatment of infectious diseases like cancer, the population of the 60-year-old has increased since 1980.

According to research, by 2050, this number will be 2 billion, leading to an increase in the number of old people with chronic degenerative health conditions like age and cancer. According to Research Gate, that is why Mikhail Blagosklonny is instrumental in the field of cancer and age research.

TOR Hypothesis

Impact Journals reported exclusively that the world jeers Mikhail Blagosklonny for his original theory on the possible action of TOR signaling, a protein that can be used to reduce aging and treat cancer. Mr. Mikhail is a New York-based scientist who studies aging and cancer at the Institute of Rosewell Park. He formulated the TOR signaling through rapamycin, a prominent cancer drug that can be used to curb age and prolong human lives.

Mikhail’s prominence roots from his passionate advocacy in the rapamycin longevity research. Rapamycin is a macrolide element used to coat coronary stents while preventing the possible rejection of an organ transplant in the bodies. It is also used to treat lymphangioleiomyomatosis, a lung disease.

Education and Career

Mikhail Blagosklonny earned his first degree and PhD in internal and experimental medicine from the First Pavlov State Medical University of St. Peterburg. In 2002, he was appointed the medicine associate professor at New York Medical College before being named the senior scientist of Ordway Research Institute in New York.

Following his passion and dedication to cancer research, treatment and therapies, Blagosklonny was appointed the professor of oncology at Rosewell Park Cancer Institute. Blagosklonny’s research capitalizes on cancer treatments that offer protection to the damaging elements of healthy cells and anti-ageing elements.

Editorial Activities

Mikhail Blagosklonny has extensive editorial activities. He is the author of hyperfunction hypothesis of ageing and anti-cancer approaches like cyclotherapy and chemotherapeutic engineering. He is the publisher of over 250 articles book chapters and cancer research reviews.

Mikhail Blagosklonny serves as the Founding Editor and Editor –in-Chief of the book Cell Cycle beside being the Co-editor of Aging, Oncoscience and Oncotarget. His vast experience led to his appointment as the Associate Editor for Cancer Biology and Therapy, Cell Death and Differentiation, The American Journal of Pathology and International Journal of Cancer.

Adam Milstein Explains His Work At Hager Pacific Properties And Philanthropy


Adam Milstein was interviewed by Ideamensch, a business ideas blog that has asked many entrepreneurs about how they got into business. Adam Milstein is a Managing Partner of Hager Pacific Properties and the Chairman of the Milstein Foundation, the Israeli-American Council, and several other non-profit organizations. Ideamensch wanted to know more about how Milstein got started in the real estate business and how philanthropy has played an integral role in his career.

 

Adam Milstein would tell you the man who’s influenced his thinking the most is David Hager who he co-founded Hager Pacific Properties with. It’s largely because Milstein admires those who are great thinkers and will take the steps to solve problems that nobody else will. Milstein got into the real estate business upon completing his MBA at USC and made his own way towards becoming an investor and asset manager because he was unhappy with the other opportunities he was presented with. Milstein likes the unpredictable nature of the real estate market and seems to care less about having routine in his day than about just doing his best with any situation that comes his way. He does encourage entrepreneurs entering the real estate industry to be patient and follow up constantly with their contacts.

 

Adam Milstein has made the Jerusalem Post’s Top 50 Most Influential Jews list of 2016, a list that’s included famous politicians, entertainers and philanthropists including Prime Minister Benjamin Netanyahu and US Senator Chuck Schumer. He’s spoken on many university campuses and at various Jewish forums and summits, and has helped launch Jewish tradition and Hebrew learning programs for Jewish Americans. His foundation is known for three pillars in active philanthropy, path life impact and philanthropic synergy.

 

Adam Milstein was born in Israel just four years after the land was established as a new nation. His father was a building framer who also fought in the nation’s first war. Adam is the oldest of three sons and a former military veteran himself who fought under Ariel Sharon’s command in the Yom Kippur War. He holds a bachelor’s degree from the Technion, Israeli Institute of Technology where he graduated from in 1978, and he earned his MBA at USC in 1981. He and his wife Gila established the Milstein Foundation in the year 2000.

Don Ressler And Adam Goldenberg Are A Force In Fashion


 

Women’s fashion would not be the first thing that comes to most men’s minds when looking to start a new business. However, as the LA Times writes, Don Ressler and Adam Goldenberg saw tremendous opportunity when they decided to team together and launch a new organization. The idea was JustFab. JustFab is an online clothing retailer that focuses on women’s apparel. Adam and Don had no experience with working in retail or with women’s fashion. Their focus was on a new manner in which the consumers would access the product. JustFab’s business model allowed consumers to shop online and make purchases at a significantly discounted price if they joined the site as members. Membership was a monthly fee no matter if a purchase was made or not. The discounts that were available with the membership proved worth it to those who decided to join the JustFab website. The company grew rapidly. Don and Adam were forced to bring in investors in order to keep up with the insatiable demand for their new product line. JustFab is now an international selling enterprise.

Fabletics soon followed as a new concept within Don and Adams business organization. Fabletics is a line of women’s athletic clothing. The two businessmen joined forces with actress Kate Hudson in order to promote the line. Fabletics had immediate success. Don and Adam looked to diversify the marketing plan for the new athletic line. Eventually they decided to open retail stores in specific locations in order to provide consumers with the opportunity to physically browse the items they were shopping for. Material that is purchased inside of a store is logged into a shoppers membership profile the same way it is if they had bought the item online. The profile keeps track of a shoppers buying tendencies and recommends new products for them on a periodic basis. This concept was put in place in order to keep members actively involved in the website.

Don Ressler and Adam Goldenberg met at Intermix when they were both young executive within the company. Adam had founded a startup company called Gamers Alliance and sold it to Intermix for millions of dollars. He was the youngest executive at the company along with Don Ressler who had also sold his startup company known as Fitness Heaven. Intermix was bought out by another corporation. Don and Adam decided that it was in their best interest to leave the company and become partners in a venture of their own.  Check out Don Ressler on LinkedIn for another window into what he has planned next for his career and his companies

Brad Reifler Tells Investors How They Can Avoid The Real Money Monster


Money Monster, one of the biggest box office hits of 2016 is not fully based on a true story, though some people’s experiences have played into the story that unfolds. But Brad Reifler has seen it and as an investment advisor and business leader who’s familiar with the dealings of Wall Street, he certainly has seen corruption that has played out similarly to the movie. He’s been working to change the culture surrounding investing, and he took the liberty to tell investors how to avoid the real money monsters out there.

Brad Reifler says first of all that investors should not simply invest in the stock market. It does have high profits for stocks that do well, but it’s also highly risky and could lead to major losses. He also says portfolio managers must stop making profits regardless of how well investor funds perform, and calls for greater accountability for them and for investors to do research on their manager. And he also says investors can only truly do well if they stick to their investing goals.

Brad Reifler began his investing career after graduating from Bowdoin College. In 1982, he started Reifler Trading Company which he managed for nearly 20 years. He started as a global derivatives and discretionary funds company and turned it to a large futures investment firm. He also founded Pali Capital in 1995 and turned that company into an international hedge fund investment company, opening offices in several other countries overseas. He founded Forefront Capital, his current company in 2009 and has setup several subsidiaries along with it.

Brad Reifler started Forefront with the intention of building a portfolio of top 1% clients, but he soon moved to smaller income and unaccredited investors after realizing how important they were to investing. He worked with the SEC to change regulations allowing unaccredited investors into an alternative fund. A little over a year ago, he established Forefront Income Trust to allow investors to invest in a Fund Shares or IRA for as little as $1,000.

Sam Tabar’s Impact on the Financial World


A well known and respected attorney, Sam Tabar has been making an impact on the business world. A graduate of the prestigious Oxford University and Columbia Law School, Tabar has had an incredible career that is admired by many. Throughout his career, Tabar has worked with top companies like Bank of America, Merrill Lynch and PMA Investment Advisors. After years of success he continues to impact a large number of people.

After graduating from law school, Sam Tabar served as Associate Editor of the Columbia Business Law Review. He has worked for years counseling clients on hedge funds and investment management agreements. From there he would move to work with PMA Investment Advisers where he managed a $2 billion hedge fund. Throughout this time he was able to develop a rolodex of more than 2000 investors. In addition he led the company to raise more than one billion dollars all while under his management.

Just a few years later Tabar moved on to work with Bank of America. It was here he became the head and director of capital strategy. He worked specifically with the Asian pacific area. He continued to counsel clients on hedge funds and other investments. His rolodex also continued to flourish during this time. A few years later, Tabar joined forces with Schulte Roth & Zabel LLP as a Senior Associate catering to hedge funds. During this time he spent more than a year providing guidance to clients on fund formation and structure, investment management agreements and many other investments.

Tabar holds other talents outside of his investment knowledge. He is fluent in multiple languages including French and Japanese. He also is a frequent traveler and event planner. Sam Tabar’s work is admired by many in his field and he is an example for anyone attempting to begin a career in the law field.

Just Who Is Clay Siegall & What Does He Do?


If you’re not too familiar with cancer research then you probably won’t recognize the name in this article, but this article is a great place to educate you on a very special individual. This individual has changed the game when it comes to the fight against cancer and his organization firmly sits at the top of the apex thanks to it’s great products and services. Clay Siegall is the name in question and Seattle Genetics is the organization he represents. Clay Siegall is by far one of the biggest names in cancer research and has been for some time now. He has led this valiant fight for many years while working with many high profile organizations such as Bristol Myers Squibb, The National Institute of Health, as well as The National Cancer Institute.

 

Clay Siegall has many titles thanks to his broad educational background. He’s known to be a scientist, philanthropist, guest speaker, fund raiser, and doctor. This brilliant minded individual attended the University of Maryland where obtained a (BS) in Zoology. The good doctor also earned a Ph.D in Genetics from the prestigious George Washington University. With all of these accomplishments you would think that he would be a household name, but unfortunately that isn’t the case. Dr. Siegall isn’t in it for fame, he’s in it to save lives and his company Seattle Genetics produces some of the best antibody based therapies in the business. These breakthrough therapies are known as (ADCs) aka Antibody Drug Conjugates. They specifically target cancerous cells within the body and attacks them with cell killing agents. This method is much more efficient as it spares all non-targeted cells within the body which cuts down on nasty side effects.

 

HeraldNet News reported that Seattle Genetics will be hiring at least 200 more employees in the near future in part by it’s huge growth. This will bring the company’s total up to around 1,100 in all. Dr. Siegall is the man in charge and will continue to see this progression through to the end.

Clay Siegall & His Leadership At Seattle Genetics


Cancer Research is a popular and profitable industry that has come a long way over the years. Even though cancer itself is still prevalent in today’s society, the future is looking much more brighter thanks to some innovative medications and the ingenuity of Clay Siegall. Clay Siegall is widely known as a doctor, scientist, guest speaker, and philanthropist. He is the current CEO and President as well as Founder of Biotech Company Seattle Genetics. This guy has a strong backing of support within the industry and he’s well respected among his peers thanks to his brilliance. The way he implements his thoughts, ideas, and actions into play should be admired as he’s laid the blueprint to success in this field.

 

The good doctor has a heart of gold and spends most of his time helping others. Having such compassion is another reason that he is known as a philanthropist. Dr. Siegall has taken this organization straight to the top as Seattle Genetics is now a major player in the fight against cancer. Over the past few years Forbes had it on it’s list of the fastest growing companies in America. The Bothell, Washington based organization was visited by Vice president Joe Bidden early last year in part by it’s great success and news headlines. This “one-two punch” of excellence is giving cancer all it can handle and the great thing about it that there are many more drugs in the pipeline being tested for future reference. The company’s flagship drug (ADCETRIS) is setting new trends from it’s effectiveness. It has made hundreds of millions of dollars in the U.S. and Canada alone.

 

Dr. Clay Siegall has also helped to raise $1.2 Billion (via) private and public funding which go to future projects while helping to sustain the business. As you can see, the outlook in cancer research is much more positive and the world owes much of the credit to Dr. Clay Siegall.

Danilo Diaz Granados Delights South Florida with Special Event


Danilo Diaz Granados entertained visitors from a variety of reputable organizations on July 19, 2016 in Miami, Florida. The sensational itinerary mixed adventure with luxury in a one of a kind experience fit for Miami’s finest.

The day began with breakfast Dame Zaha Hadid’s One Thousand Museum sales center. The upcoming residential center located in the Biscayne area exemplifies high class living, and guests were honored with a special tour. A half hour helicopter ride around the Palm Beach Race track took place after breakfast. Lunch featured Dom Perignon champagne. The company sponsored the event, and lunch was served at the River Boat Yacht Club, located on the Miami river.

While the sun went down, guests had the opportunity to take brand new boats out for a spin, thanks to the help of sponsors Technomar and Von Dutch. The unique opportunity to fly and enjoy the water exemplified Toys for Boys mission for high class living and memorable experiences. The day was altogether sensational, and was put on with the help of various sponsors such as Air Commander Aerospace, One Thousand Museum, and Gryphon Racing.

The host Danilo Diaz Granados graduated Babson college with a degree in Economics and Entrepreneurship. He also holds an MBA in Business Administration. Focusing on the needs of Latin American men to have luxury living, he opened his boutique Toys for Boys in Miami. It features high-end cars, watches, contemporary art and fashion which exemplifies class in South Florida and the world. Granados offers the men of Miami unique products fit for a king.

Essence Of True Nobility


George Soros is an artist at living, His work of art being his esteemed life. Being a native to Hungary he moved to England in 1947 and secured work shortly after graduation as an investment banker. He eventually moved to New York as he rose through the ranks to become a sort after investment manager on time.com. He eventually branched off to establish his own company later named THE HEDGE FUND and solidifying his position as the greatest investment managers of the modern era.

George Soros later distant himself from the intrigues of the financial markets to invest in people as true living means we can be responsive to the other person. This was achieved through his widely credited OPEN SOCIETY social platform currently involved in various project well spread over 100 countries. This philanthropic projects range from basic human rights to education of native Africans under apartheid to fighting the spread of communism in Eastern Bloc by facilitating the reproduction of restricted texts. His passion for progressive on nytimes.com change led to adoption of transparency virtues in the extraction industries especially those directly involved with natural resources resulting in profit driven conflicts. His dedication to human rights activism has seen him voice his opinion in regards to asylum seekers from the Syria. He details a comprehensive plan policy that is far less disruptive and cheaper in the long run that can easily be adopted by the EU which maintains human dignity.

Democracy connotes debate and dissent, and as a stern democrat he was influential in bankrolling a legal battle against voting laws effected by the government administration of George W. Bush. The restrictive measures included nullification of ballots that might have been cast in different precincts as well as early voting that would effectively make casting of votes hectic during weekends presiding the election date on project-syndicate.org. This was his initial involvement in political matters in America.

Respect for law like any perishable commodity can be lost if not nourished and as such George Soros has been on the frontier voicing his displeasure to the injustices being committed by Russia’s president Putin to the people’s government of Ukraine under the watchful eye of the European and American administration at http://www.theatlantic.com/magazine/archive/1997/02/the-capitalist-threat/376773/. He creates his own sub-culture of going against the herd by valuing the less privileged in society stating the potential tragic and far-reaching geopolitical effects that might result from the erosion of Ukraine’s independence and the growing influence of a Victorious Putin Administration if left unchecked in Europe. Leading to a predictable military confrontation between the nations involved although Russian aggression will negatively impact on the simulative effect in greater European countries. Such a blunt exchange will have few benefits, reducing the pressure on currency to settle with the bond holders as well as lowering the interest risk on premiums. He continues to advocate for the eradication of corruption in Ukraine’s black hole reducing the chances of a potential sovereign default hence persuading more cash injection to Ukraine’s economy by its foreign bank shareholders.

So Many People Are Now Getting To Know About FreedomPop Services


FreedomPop has become known by many because of everything that they are offering to their customers. With so many people looking for a better way to obtain wireless services, without having to pay high prices, many are finding that FreedomPop has everything that they are looking for. With free cell phone services as well as low-cost paid services, FreedomPop can accommodate anyone with any kind of wireless needs. Take a FreedomPop review for instance, many of them will talk specifically about the free phone service because it’s one of their longest-running programs.

 

The free service doesn’t come with a cell phone but can have one shipped out to the customer by having them pay for it on the FreedomPop website. With a cell phone costing as little as $10, it’s easy for anyone to get a smartphone that they love from FreedomPop. Even though the free service has been around for a while, things have changed, including the amount of the services that are being offered with the free plan. There are 200 minutes of talk time, 500 MB of data, and the text messages are unlimited with the free service.

 

Anyone who has chosen the free service can use it on one of two types of phones, which is a GSM phone or a CDMA phone from Sprint. Those who are going to use a GSM phone must first ensure that the network lock is completely removed, allowing it to be used on the FreedomPop network. Also, a FreedomPop sim card must be obtained from the company to use it any GSM phone, regardless of which plan is chosen. Speaking of choices, there are several other cell phone service choices, such as the paid plan for $10.99.

 

The paid plan is very popular because of the unlimited talk and text, but there is only 500 MB of data included with this plan. Adding the FreedomPop Wi-Fi service plan to a cell phone for only five dollars per month will give unlimited data to anyone who is in need of it, especially if they don’t have the unlimited everything plan. The $19.99 unlimited everything plan is truly the most popular plan from FreedomPop because it has unlimited data as well as unlimited talk and text. The unlimited everything plan can also be used with a Sprint phone as well as a GSM phone that takes a sim card.